# Ketogenic diet clinical trial results > Live situation record from CLSTR: https://clstr.news/situations/20260912-ketogenic-diet-clinical-trial-results > Updated: 2026-09-12T14:37:00.000Z. Sources: 6. Developments: 2. A clinical trial published in Cell Metabolism suggests that a ketogenic diet may be more effective at reducing liver fat and reversing prediabetes than Mediterranean or plant-forward diets. The study involved adults with obesity, prediabetes, and fatty liver disease who were guided to lose approximately 10% of their starting body weight. While all dietary groups achieved similar weight loss, the ketogenic group—characterized by 73% fat and 4% carbohydrate intake—showed superior metabolic improvements. Specifically, participants on the ketogenic diet experienced an average 67% reduction in liver fat, compared to approximately 45% in the Mediterranean and plant-forward groups. Additionally, 50% of the ketogenic group no longer met the criteria for prediabetes by the end of the study, whereas 29% of the Mediterranean group and 7% of the plant-based group achieved the same result. Researchers noted that the ketogenic diet may trigger an increase in glucagon, a hormone that assists in removing fat from the liver. ## Timeline ### 2026-09-12: Ketogenic diet more effective at reversing prediabetes, study finds A Washington University study finds that a ketogenic diet is more effective than Mediterranean or plant-based diets at reversing prediabetes and reducing liver fat in adults with obesity. 3 sources. https://clstr.news/cluster/ketogenic-diet-more-effective-at-reversing-prediabetes-study-finds ### 2026-09-09: Ketogenic diet reduces liver fat by 67% in clinical trial A clinical trial found that a ketogenic diet reduced liver fat by 67% in adults with obesity and prediabetes, outperforming Mediterranean and plant-forward diets despite similar total weight loss. 3 sources. https://clstr.news/cluster/ketogenic-diet-reduces-liver-fat-by-67-in-clinical-trial-1 --- Cite as: Ketogenic diet clinical trial results. CLSTR, https://clstr.news/situations/20260912-ketogenic-diet-clinical-trial-results