# Cardiovascular and metabolic disease risk research > Live situation record from CLSTR: https://clstr.news/situations/cardiovascular-and-metabolic-disease-risk-research > Updated: 2026-08-22T11:02:58.000Z. Sources: 11. Developments: 2. Recent medical research highlights the prevalence and interconnectedness of cardiovascular, metabolic, and kidney (CKM) risk factors across different age groups. A large-scale study involving over nine million people in South Korea and 7,000 in the United States found that nearly 99 percent of individuals who suffered major cardiovascular events had at least one unmanaged risk factor, such as high blood pressure, elevated cholesterol, high blood glucose, or smoking. Further research focusing on younger populations indicates that 80 percent of young adults, with an average age of 23, exhibit early signs of CKM disease. Experts note that because many of these indicators are asymptomatic, early lifestyle interventions—including healthy eating, regular exercise, and tobacco avoidance—are essential for prevention before conditions progress to established cardiovascular disease. ## Timeline ### 2026-08-22: Research shows 80% of young adults exhibit early cardiovascular and metabolic risk signs Research shows 80% of young adults exhibit early signs of cardiovascular, kidney, or metabolic disease, highlighting the need for early health monitoring and lifestyle interventions. 4 sources. https://clstr.news/cluster/research-shows-80-of-young-adults-exhibit-early-cardiovascular-and-metabolic-risk-signs ### 2026-08-22: Cardiovascular risk factors precede nearly all major heart events A study of millions shows 99% of major cardiovascular events are preceded by risk factors like high blood pressure, cholesterol, or smoking, highlighting the importance of early detection and lifestyle changes. 7 sources. https://clstr.news/cluster/cardiovascular-risk-factors-precede-nearly-all-major-heart-events --- Cite as: Cardiovascular and metabolic disease risk research. CLSTR, https://clstr.news/situations/cardiovascular-and-metabolic-disease-risk-research