# Diabetes health risks and medication complications > Live situation record from CLSTR: https://clstr.news/situations/diabetes-health-risks-and-medication-complications > Updated: 2026-09-01T20:04:07.000Z. Sources: 4. Developments: 2. Medical research has highlighted various health complications and risks associated with diabetes and its treatments. Studies utilizing Medicare data indicated that glucagon-like peptide-1 receptor agonists (GLP-1RAs) may be linked to increased risks of kidney and endometrial cancers when compared to other medications. Additionally, a review of clinical trials found that sodium-glucose cotransporter 2 inhibitors (SGLT2is) are associated with a higher incidence of genital infections. Further research in England has identified that infection is a leading underlying cause of death for individuals with type 2 diabetes, following cardiovascular disease and cancer. The risk of hospitalization due to infection is notably higher for those with type 1 diabetes. To mitigate these risks, studies suggest that adherence to an ‘ideal’ lifestyle—including regular physical activity, adequate sleep, and not smoking—can significantly reduce the incidence of infections, including pneumonia and sepsis. ## Timeline ### 2026-09-01: Diabetes increases infection and mortality risks Studies show diabetes significantly increases infection and mortality risks, but adhering to a healthy lifestyle may reduce infection incidence in type 2 diabetes patients by approximately 44 percent. 2 sources. https://clstr.news/cluster/diabetes-increases-infection-and-mortality-risks ### 2026-08-28: Diabetes medications linked to increased cancer and infection risks Medical studies link GLP-1 receptor agonists to increased kidney and endometrial cancer risks, while SGLT2 inhibitors are associated with a higher risk of genital mycotic infections in diabetes patients. 2 sources. https://clstr.news/cluster/diabetes-medications-linked-to-increased-cancer-and-infection-risks --- Cite as: Diabetes health risks and medication complications. CLSTR, https://clstr.news/situations/diabetes-health-risks-and-medication-complications