# First Complete Human Diploid Genome

> Live situation record from CLSTR: https://clstr.news/situations/first-complete-human-diploid-genome
> Updated: 2026-08-06T23:28:19.000Z. Sources: 6. Developments: 2.

In early August 2026, an international research team announced the first fully sequenced human diploid genome, reconstructing both maternal and paternal chromosome sets from telomere to telomere. The achievement completed the remaining ~8 % of the genome that the original Human Genome Project left unread and built on the 2022 Telomere‑to‑Telomere (T2T) effort, which had produced a haploid reference.

The consortium released twelve papers describing the new reference, which adds roughly 15 % (about 900 million bases) of DNA previously missing, including regions linked to cancer, heart disease, and neurological disorders. Researchers highlighted the impact on personalized medicine, noting that sequencing costs have fallen dramatically—from the $4.3 billion of the original project to about $5,000 per genome. The work also involved sequencing eight other vertebrate species to train AI models for deeper biological insight.

## Timeline

### 2026-08-06: Telomere-to-Telomere Consortium completes first full human genome

The T2T Consortium has built the first complete human genome from a real donor, adding 15 % new DNA and cutting sequencing costs to about $5,000, paving the way for personalized medicine.

2 sources. https://clstr.news/cluster/telomere-to-telomere-consortium-completes-first-full-human-genome

### 2026-08-06: Scientists complete first fully sequenced human diploid genome

A team from Johns Hopkins, NIH and NIST completed the first fully sequenced diploid human genome, filling the last 8 % missing from the original project and paving the way for personalized medicine.

4 sources. https://clstr.news/cluster/scientists-complete-first-fully-sequenced-human-diploid-genome

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Cite as: First Complete Human Diploid Genome. CLSTR, https://clstr.news/situations/first-complete-human-diploid-genome