# Fractyl Health Revita weight loss study progress > Live situation record from CLSTR: https://clstr.news/situations/fractyl-health-revita-weight-loss-study-progress > Updated: 2026-08-10T20:56:25.000Z. Sources: 2. Developments: 2. Fractyl Health has reported positive long-term data regarding its Revita endoscopic procedure, designed to help patients maintain weight loss after discontinuing GLP-1 therapy. Initial one-year results from the REMAIN-1 study's Midpoint Cohort indicated that the Revita DMR System reduced weight regain by approximately 40% compared to a sham procedure. Specifically, patients with complete duodenal ablation of more than 14 cm maintained roughly 81% of their GLP-1-induced weight loss, whereas the sham group maintained only 48%. The company noted that 73% of Revita patients met the FDA-mandated performance goal of maintaining at least a 5% total body-weight loss. As the company progresses with its REMAIN-1 pivotal trial involving over 300 participants, it aims to release topline six-month data from the larger pivotal cohort in early Q4 2026. Fractyl Health is also targeting a potential FDA De Novo marketing application later in that quarter. ## Timeline ### 2026-08-10: Kornit Digital and Fractyl Health report quarterly updates Kornit Digital beat Q2 earnings estimates with $55.3 million in revenue, while Fractyl Health reported that its Revita procedure helps patients maintain weight loss after stopping GLP-1 therapy. 2 sources. https://clstr.news/cluster/kornit-digital-and-fractyl-health-report-quarterly-updates ### 2026-07-15: Fractyl Health reports 1‑year REMAIN‑1 data showing sustained weight loss after GLP‑1 therapy Fractyl Health's REMAIN‑1 data showed the Revita system cut weight regain by 40%, with 73% of patients keeping ≥5% loss, exceeding FDA goals; no serious adverse events and shares rose 8%. 3 sources. https://clstr.news/cluster/fractyl-health-reports-1year-remain1-data-showing-sustained-weight-loss-after-glp1-therapy --- Cite as: Fractyl Health Revita weight loss study progress. CLSTR, https://clstr.news/situations/fractyl-health-revita-weight-loss-study-progress