# Health impacts of sugar substitutes research > Live situation record from CLSTR: https://clstr.news/situations/health-impacts-of-sugar-substitutes-research > Updated: 2026-09-22T10:19:08.000Z. Sources: 4. Developments: 2. Scientific research is re-evaluating the health impacts of sugar substitutes and sugar-free chewing gum. A review conducted by researchers from the University of Ljubljana, Wageningen University & Research, and the University of Leeds suggests that replacing sugar with non-nutritive sweeteners does not appear to damage weight control or cardiometabolic health. Synthesizing evidence from the SWEET, SWITCH, and Sweet Tooth research consortia, the findings challenge previous concerns that artificial sweeteners might increase cravings for sweets or lead to higher caloric intake. Graham Finlayson, a psychologist at the University of Leeds, noted that results from randomized controlled trials differ from earlier studies that had linked these substitutes to negative health outcomes. In the oral health sector, industry developments include efforts by Perfetti Van Melle to share clinical evidence regarding the benefits of sugar-free gum, specifically its role in stimulating saliva production. ## Timeline ### 2026-09-22: Research review finds no link between sweeteners and weight gain A research review involving several European universities found no evidence that artificial sweeteners hinder weight loss or harm heart health, contrary to previous concerns. 2 sources. https://clstr.news/cluster/research-review-finds-no-link-between-sweeteners-and-weight-gain ### 2026-09-15: Research examines health impacts of sugar substitutes and sugar-free gum New research suggests sugar substitutes may not harm weight or metabolic health, while industry studies highlight the oral health benefits of sugar-free chewing gum. 2 sources. https://clstr.news/cluster/research-examines-health-impacts-of-sugar-substitutes-and-sugar-free-gum --- Cite as: Health impacts of sugar substitutes research. CLSTR, https://clstr.news/situations/health-impacts-of-sugar-substitutes-research