# Hepatitis B research and treatment development

> Live situation record from CLSTR: https://clstr.news/situations/hepatitis-b-research-and-treatment-development
> Updated: 2026-09-11T20:15:44.000Z. Sources: 5. Developments: 2.

Efforts to develop treatments and a cure for hepatitis B have emerged through both large-scale international research and specific technological developments.

A global research consortium led by Johns Hopkins University has launched a five-year study involving researchers from the United States, Brazil, India, Senegal, and Uganda. The initiative aims to monitor 600 patients to observe viral behavior and immune responses, with the long-term goal of eliminating hepatitis B as a public health problem by 2030.

In a separate development, Sechenov University and R-Pharm have begun developing a gene-editing treatment using CRISPR-Cas9 technology. Supported by the Academician E.P. Velikhov grant, this approach utilizes biocompatible nanoparticles to target viral DNA in liver cells. The goal of this method is to achieve a complete cure via a single injection while minimizing risks to the human genome.

## Timeline

### 2026-09-11: Sechenov University begins Hepatitis B gene-editing drug development

Sechenov University and R-Pharm are developing a CRISPR-Cas9 based treatment for Hepatitis B that aims to cure the virus with a single injection using nanoparticle delivery.

2 sources. https://clstr.news/cluster/sechenov-university-begins-hepatitis-b-gene-editing-drug-development

### 2026-09-01: Global research consortium seeks hepatitis B cure

A global research consortium led by Johns Hopkins University is studying hepatitis B and HIV co-infection to find new treatments and a potential cure, involving researchers from Brazil, India, Senegal, and ug.

3 sources. https://clstr.news/cluster/global-research-consortium-seeks-hepatitis-b-cure

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Cite as: Hepatitis B research and treatment development. CLSTR, https://clstr.news/situations/hepatitis-b-research-and-treatment-development