# Impact of exercise on cognitive and biological health

> Live situation record from CLSTR: https://clstr.news/situations/impact-of-exercise-on-cognitive-and-biological-health
> Updated: 2026-09-25T16:30:21.000Z. Sources: 5. Developments: 2.

Research indicates that both physical and mental exercises provide significant biological and cognitive benefits. Physical activity is linked to the ‘runner’s high’ and reduced anxiety, likely driven by the endocannabinoid system. Furthermore, movement such as walking or cycling can enhance creativity, promote the growth of the hippocampus, and increase the production of Brain-derived neurotrophic factor (BDNF), which is essential for nerve cell networking.

Regarding mental stimulation, studies suggest that targeted digital training can influence brain biology. For instance, mental exercises designed to stimulate attention and processing speed have been shown to increase activity in the cholinergic system, specifically within the hippocampus and cingulate cortex. Such interventions may mitigate cognitive decline, potentially making the brain function similarly to that of a person ten years younger.

## Timeline

### 2026-09-25: Physical activity linked to improved cognitive performance and creativity

Research shows that regular physical activity, even in moderate amounts, enhances creativity, supports brain health through BDNF production, and can promote hippocampal growth.

3 sources. https://clstr.news/cluster/physical-activity-linked-to-improved-cognitive-performance-and-creativity

### 2026-08-31: Physical and mental exercises impact biological health and cognition

Research indicates that physical activity can trigger euphoria via the endocannabinoid system, while targeted digital cognitive training may rejuvenate brain function in older adults.

2 sources. https://clstr.news/cluster/physical-and-mental-exercises-impact-biological-health-and-cognition

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Cite as: Impact of exercise on cognitive and biological health. CLSTR, https://clstr.news/situations/impact-of-exercise-on-cognitive-and-biological-health