# Low-dose radiation therapy clinical research > Live situation record from CLSTR: https://clstr.news/situations/low-dose-radiation-therapy-clinical-research > Updated: 2026-10-21T13:30:55.000Z. Sources: 6. Developments: 2. Research into low-dose radiation therapy has expanded across several medical applications. Initial findings presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting demonstrated the efficacy of ultra-low-dose radiation for treating painful bone lesions in multiple myeloma patients, with 81% achieving pain control. Additionally, a long-term analysis indicated that low-dose radiation provides sustained improvements in pain and physical function for patients with knee osteoarthritis, showing a 67% lower hazard of disability compared to medication alone. Building on these developments, Mayo Clinic researchers have launched a new clinical trial to investigate the use of low-dose radiation as an anti-inflammatory approach for early-stage Parkinson’s disease. This study aims to target underlying biological processes in the brain rather than focusing solely on symptom management. ## Timeline ### 2026-10-21: Mayo Clinic researchers study low-dose radiation for Parkinson’s Mayo Clinic is conducting a first-of-its-kind clinical trial using low-dose radiation to target brain inflammation and potentially slow the progression of early-stage Parkinson’s disease. 2 sources. https://clstr.news/cluster/mayo-clinic-researchers-study-low-dose-radiation-for-parkinsons ### 2026-09-27: Low-dose radiation therapy shows promise for myeloma and osteoarthritis Clinical studies presented at the ASTRO Annual Meeting show that low-dose radiation therapy can effectively relieve pain from multiple myeloma bone lesions and potentially slow the progression of knee disease. 5 sources. https://clstr.news/cluster/low-dose-radiation-therapy-shows-promise-for-myeloma-and-osteoarthritis --- Cite as: Low-dose radiation therapy clinical research. CLSTR, https://clstr.news/situations/low-dose-radiation-therapy-clinical-research