# NFL preseason and regular season betting trends

> Live situation record from CLSTR: https://clstr.news/situations/nfl-preseason-and-regular-season-betting-trends
> Updated: 2026-09-18T11:04:47.000Z. Sources: 6. Developments: 3.

NFL betting trends transitioned from the preseason into the start of the regular season. During preseason Week 2, underdogs and road teams showed statistical success, with underdogs leading cumulative preseason statistics 18-13-1 straight up.

As the regular season commenced, Week 1 results began influencing Week 2 betting markets. In the first week of regular play, favorites performed well with an 11-4 straight up record. Notable shifts in betting lines occurred following high-scoring performances, such as the Chicago Bears' 59-point game, and player availability, including the return of Patrick Mahomes from an ACL injury.

Heading into Week 2, markets are reacting to specific Week 1 outcomes. The Chicago Bears' betting line moved from as high as -6.5 to -5.5 following their performance against Carolina. Other notable Week 1 events included Arizona’s victory as a 9.5-point underdog against the Chargers, and the Minnesota Vikings defeating Green Bay 39-22 after Vikings quarterback Kyler Murray suffered a concussion.

For Week 2 matchups, analysts are identifying specific value plays. For the Monday Night Football game between the Denver Broncos and Kansas City Chiefs, suggestions include backing the Chiefs on the moneyline, citing the presence of Kenneth Walker III. In other matchups, predictions suggest value in the Cincinnati Bengals moneyline due to the potential of Joe Burrow and J’Marr Chase, while some analysts favor the Green Bay Packers to rebound against the New York Jets despite their previous loss.

## Timeline

### 2026-09-18: NFL Week 2: Betting predictions and underdog picks

NFL Week 2 betting analysis highlights potential underdog value for the Cincinnati Bengals and a projected rebound for the Green Bay Packers against the New York Jets.

2 sources. https://clstr.news/cluster/nfl-week-2-betting-predictions-and-underdog-picks

### 2026-09-14: NFL Week 2 betting lines shift following Week 1 results

NFL Week 2 betting lines are shifting following Week 1, with focus on the Broncos-Chiefs Monday Night Football game and the Chicago Bears' recent high-scoring performance.

4 sources. https://clstr.news/cluster/nfl-week-2-betting-lines-shift-following-week-1-results

### 2026-08-26: NFL preseason Week 2 betting trends show underdog success

NFL preseason Week 2 betting trends show underdogs and road teams performing strongly against the spread.

2 sources. https://clstr.news/cluster/nfl-preseason-week-2-betting-trends-show-underdog-success

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Cite as: NFL preseason and regular season betting trends. CLSTR, https://clstr.news/situations/nfl-preseason-and-regular-season-betting-trends