# Radioactive glue treatment for pancreatic cancer

> Live situation record from CLSTR: https://clstr.news/situations/radioactive-glue-treatment-for-pancreatic-cancer
> Updated: 2026-10-09T12:00:16.000Z. Sources: 11. Developments: 2.

Doctors at Fondazione Policlinico Gemelli in Rome have performed the first global clinical application of a specialized radioactive biological glue to treat inoperable pancreatic cancer. The procedure, which utilized YntraDose® developed by the Italian startup BetaGlue Therapeutics, involved injecting a substance containing Yttrium-90 particles directly into a 63-year-old woman’s tumor.

This minimally invasive percutaneous therapy is designed to shrink tumor mass through targeted infiltration, with the goal of making locally advanced cancers eligible for traditional surgery at a later stage. The one-hour procedure was performed under local anesthesia and minimal sedation. Initial follow-up PET-CT scans confirmed the radiopharmaceutical was correctly deposited within the pancreas without off-target uptake.

The treatment was conducted as part of an international clinical trial involving medical oncology experts. The trial includes participating institutions across Italy, Belgium, and Great Britain, with further patient administrations scheduled for October.

## Timeline

### 2026-10-09: Gemelli Hospital performs first global use of radioactive glue for pancreatic cancer

The Policlinico Universitario A. Gemelli in Rome has completed the first global use of YntraDose, a radioactive biological glue intended to shrink inoperable pancreatic tumors.

5 sources. https://clstr.news/cluster/gemelli-hospital-performs-first-global-use-of-radioactive-glue-for-pancreatic-cancer

### 2026-10-03: Fondazione Policlinico Gemelli performs world-first inoperable pancreatic tumor treatment

Physicians at Fondazione Policlinico Gemelli have performed the first-ever treatment of an inoperable pancreatic tumor using a radioactive biological glue to potentially enable future surgery.

6 sources. https://clstr.news/cluster/fondazione-policlinico-gemelli-performs-world-first-inoperable-pancreatic-tumor-treatment

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Cite as: Radioactive glue treatment for pancreatic cancer. CLSTR, https://clstr.news/situations/radioactive-glue-treatment-for-pancreatic-cancer
