# Research on intensive blood pressure reduction > Live situation record from CLSTR: https://clstr.news/situations/research-on-intensive-blood-pressure-reduction > Updated: 2026-10-19T10:21:10.000Z. Sources: 4. Developments: 2. A meta-analysis of 27 studies involving approximately 90,000 participants indicates that intensive blood pressure reduction significantly lowers the risk of heart attacks and strokes. Research published in JAMA Cardiology shows that for every 10 mmHg reduction in systolic blood pressure, the risk of major cardiovascular events decreases by approximately 15%. These cardiovascular benefits were observed in individuals both with and without chronic kidney disease. While intensive treatment was associated with a higher relative likelihood of sustained decreases in the estimated glomerular filtration rate (eGFR), the analysis found no increased risk of actual kidney failure requiring dialysis or transplantation. ## Timeline ### 2026-10-19: Intensive blood pressure treatment reduces cardiovascular risks A review of 27 clinical trials shows that intensive blood pressure treatment significantly reduces major cardiovascular risks without increasing kidney failure. 2 sources. https://clstr.news/cluster/intensive-blood-pressure-treatment-reduces-cardiovascular-risks ### 2026-10-15: Blood pressure studies link intensive reduction to heart protection New research shows intensive blood pressure reduction significantly lowers heart attack and stroke risks without increasing kidney failure, while medical guidelines define 90 mmHg diastolic as the hypertensioné–¾ 2 sources. https://clstr.news/cluster/blood-pressure-studies-link-intensive-reduction-to-heart-protection --- Cite as: Research on intensive blood pressure reduction. CLSTR, https://clstr.news/situations/research-on-intensive-blood-pressure-reduction