# Wellness supplement impacts on hormonal health

> Live situation record from CLSTR: https://clstr.news/situations/wellness-supplement-impacts-on-hormonal-health
> Updated: 2026-08-16T19:32:26.000Z. Sources: 6. Developments: 2.

Research and scrutiny regarding wellness supplements have highlighted potential adverse effects on hormonal balance and libido. Melatonin, commonly used as a sleep aid, has been linked to side effects such as headaches, decreased blood pressure, and lethargy. There are specific concerns that melatonin may interfere with the hypothalamic-pituitary-gonadal (HPG) axis, potentially suppressing reproductive hormones like luteinizing hormone.

Other supplements, including saw palmetto, St. John’s wort, licorice root, and saw palmetto, are also noted for their potential to impact hormonal health or inadvertently decrease sexual interest.

## Timeline

### 2026-08-16: Supplements like melatonin and saw palmetto may impact libido

Common wellness supplements like melatonin and saw palmetto may inadvertently lower libido by affecting hormone levels and the hypothalamic-pituitary-gonadal axis.

3 sources. https://clstr.news/cluster/supplements-like-melatonin-and-saw-palmetto-may-impact-libido

### 2026-08-16: Melatonin supplements linked to side effects and hormonal changes

Melatonin and other dietary supplements are under scrutiny for potential side effects, including headaches, blood pressure changes, and possible impacts on libido due to hormonal interference.

3 sources. https://clstr.news/cluster/melatonin-supplements-linked-to-side-effects-and-hormonal-changes

---
Cite as: Wellness supplement impacts on hormonal health. CLSTR, https://clstr.news/situations/wellness-supplement-impacts-on-hormonal-health