3D Mammography shows potential in reducing interval breast cancer cases

3D mammography breast cancer screening tomosynthesis University of Münster interval cancer

A large German study suggests that 3D mammography, also known as tomosynthesis, may be more effective at early breast cancer detection than traditional 2D methods. Research led by Stefanie Weigel from the University of Münster, published in The Lancet Oncology, indicates that 3D mammography could reduce the occurrence of interval cancers—cases where tumors are diagnosed shortly after a clear screening.

In the study conducted between 2018 and 2020, 99,689 women aged 50 to 70 participated across 17 screening sites in North Rhine-Westphalia and Lower Saxony. The findings showed a 29 percent relative reduction in invasive interval cancer cases during the first year, with 4.5 cases per 10,000 women in the tomosynthesis group compared to 6.3 in the traditional mammography group.

While the 3D method uses multiple X-ray images from different angles to create thin layers that prevent tissue overlap, researchers noted that the statistical difference could not be clearly confirmed over a two-year period.

Entities

Lower Saxony · North Rhine-Westphalia · Stefanie Weigel · The Lancet Oncology · University of Münster

Claims

What the coverage asserts, and how many sources carry each claim.

[○ 1 SOURCE] The comparison group in the study had 6.3 cases of invasive interval cancer per 10,000 women. lomazoma.com
[● 4 SOURCES] 3D mammography (tomosynthesis) uses multiple X-ray images from different angles to create thin image layers. lomazoma.com · www.kreiszeitung.de · www.tz.de · www.merkur.de
[○ 1 SOURCE] The study was conducted across 17 screening locations in North Rhine-Westphalia and Lower Saxony. lomazoma.com
[○ 1 SOURCE] The study included 99,689 women aged 50 to 70 between 2018 and 2020. lomazoma.com
[● 4 SOURCES] The statistical difference between the methods could not be clearly confirmed over a two-year period. lomazoma.com · www.kreiszeitung.de · www.tz.de · www.merkur.de
[● 4 SOURCES] 3D mammography showed approximately 24 percent fewer interval breast cancer cases than traditional screening in a large German study. lomazoma.com · www.kreiszeitung.de · www.tz.de · www.merkur.de
[○ 1 SOURCE] In the first year, the tomosynthesis group had 4.5 cases of invasive interval cancer per 10,000 women. lomazoma.com
[○ 1 SOURCE] The relative reduction in interval cancer cases in the first year was 29 percent. lomazoma.com