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Alzheimer's disease: Sleep patterns and cognitive signs as early warnings

New research highlights the critical link between sleep patterns and the early detection of Alzheimer's disease. Studies published in Alzheimer’s and Dementia suggest that difficulties in reaching deep REM sleep—the stage essential for memory consolidation and learning—may serve as an early warning sign of cognitive decline. Delays in entering REM sleep are associated with higher levels of amyloid and tau proteins, which are toxic proteins that accumulate in the brains of those with the disease.

Beyond sleep disruptions, medical experts identify several other early symptoms of Alzheimer's that are often mistaken for normal aging or simple forgetfulness. These include difficulty remembering recent events, confusion regarding time and place, impaired decision-making, challenges with speech or finding words, a decrease in social participation, and noticeable changes in mood or personality.

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Alzheimer's disease · University of California