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[BUSINESS] · United Kingdom, United States, Japan, China · 30 sources

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AstraZeneca beats Q2 forecasts as oncology sales rise, but Ultomiris misses late‑stage trial goal

AstraZeneca reported second‑quarter 2026 earnings that topped analyst expectations. Net profit rose by more than 2 % to about $2.51 billion, while total revenue increased 5 % to roughly $15.38 billion on a constant‑currency basis. Oncology sales grew between 15 % and 16 % year‑on‑year, driven by flagship drugs such as Tagrisso, Imfinzi, Calquence, Lynparza and Enhertu.

At the same time, the company disclosed a setback in its rare‑disease pipeline: the late‑stage trial of Ultomiris (ravulizumab) did not achieve statistical significance for event‑free survival at 26 weeks in patients with haematopoietic‑stem‑cell‑transplant‑associated thrombotic microangiopathy. A separate paediatric study showed overall survival of 87.2 % at 26 weeks and 73.4 % at 52 weeks, prompting the company to advance regulatory filings for the pediatric indication.

AstraZeneca also announced that its experimental gastric‑cancer antibody‑drug conjugate sonesitatug vedotin met its primary endpoint, delivering a statistically significant overall‑survival benefit. CEO Pascal Soriot reiterated the target of $80 billion in annual revenue by 2030. Earlier in June, data from a weight‑loss study showed the experimental pill elecoglipron produced an average 10.5 % body‑weight loss after 26 weeks and 11.8 % after 36 weeks.

Entities

AstraZeneca · AstraZeneca plc · Enlarged cancer portfolio · Pascal Soriot · Sonesitatug vedotin · Tagrisso · Ultomiris · Ultomiris (ravulizumab) · elecoglipron

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BERENBERG stuft ASTRAZENECA auf 'Buy' [www.finanznachrichten.de]