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AstraZeneca beats Q2 forecasts as oncology sales rise, but Ultomiris misses late‑stage trial goal
AstraZeneca reported second‑quarter 2026 earnings that topped analyst expectations. Net profit rose by more than 2 % to about $2.51 billion, while total revenue increased 5 % to roughly $15.38 billion on a constant‑currency basis. Oncology sales grew between 15 % and 16 % year‑on‑year, driven by flagship drugs such as Tagrisso, Imfinzi, Calquence, Lynparza and Enhertu.
At the same time, the company disclosed a setback in its rare‑disease pipeline: the late‑stage trial of Ultomiris (ravulizumab) did not achieve statistical significance for event‑free survival at 26 weeks in patients with haematopoietic‑stem‑cell‑transplant‑associated thrombotic microangiopathy. A separate paediatric study showed overall survival of 87.2 % at 26 weeks and 73.4 % at 52 weeks, prompting the company to advance regulatory filings for the pediatric indication.
AstraZeneca also announced that its experimental gastric‑cancer antibody‑drug conjugate sonesitatug vedotin met its primary endpoint, delivering a statistically significant overall‑survival benefit. CEO Pascal Soriot reiterated the target of $80 billion in annual revenue by 2030. Earlier in June, data from a weight‑loss study showed the experimental pill elecoglipron produced an average 10.5 % body‑weight loss after 26 weeks and 11.8 % after 36 weeks.
Entities
AstraZeneca · AstraZeneca plc · Enlarged cancer portfolio · Pascal Soriot · Sonesitatug vedotin · Tagrisso · Ultomiris · Ultomiris (ravulizumab) · elecoglipron
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 4 SOURCES] Ultomiris is already approved in the United States, the European Union and Japan for treating certain rare blood disorders and neurological conditions. wdez.com · jack1065.com · wsau.com · mix929.com
- [● 5 SOURCES] AstraZeneca's experimental gastric‑cancer drug sonesitatug vedotin met a key trial goal, showing a statistically significant and clinically meaningful overall‑survival improvement. wdez.com · jack1065.com · wsau.com · mix929.com · www.hospitalmanagement.net
- [● 3 SOURCES] AstraZeneca is in ongoing discussions with global health authorities about next steps for the adult indication of Ultomiris. wdez.com · jack1065.com · wsau.com
- [● 4 SOURCES] Ultomiris did not achieve statistical significance for event‑free survival at 26 weeks in HSCT‑TMA adult trial. wdez.com · jack1065.com · wsau.com · mix929.com
- [● 4 SOURCES] In a pediatric trial, Ultomiris showed overall survival of 87.2 % at 26 weeks. wdez.com · jack1065.com · wsau.com · mix929.com
- [● 4 SOURCES] In a pediatric trial, Ultomiris showed overall survival of 73.4 % at 52 weeks. wdez.com · jack1065.com · wsau.com · mix929.com
- [● 11 SOURCES] AstraZeneca aims for up to 20 new drug launches to generate $80 billion in annual revenue by 2030. wdez.com · jack1065.com · wsau.com · mix929.com · www.finanznachrichten.de · +6 more
- [● 4 SOURCES] Sonesitatug‑vedotin met its key trial goal, showing a statistically significant overall‑survival benefit in advanced gastric cancer patients. mix929.com · wdez.com · jack1065.com · wsau.com
- [● 3 SOURCES] In a June study, the experimental weight‑loss pill elecoglipron caused an average 10.5 % body‑weight loss after 26 weeks and 11.8 % after 36 weeks. entrevue.fr · es.euronews.com · www.euronews.com
- [● 6 SOURCES] Total revenue for the quarter rose 5 % at constant‑currency rates to $15.38 billion. entrevue.fr · es.euronews.com · www.finanzen.at · www.finanzen.ch · www.moneycab.com · +1 more
- [● 4 SOURCES] Ultomiris showed overall survival of 87.2 % at 26 weeks and 73.4 % at 52 weeks in a paediatric study. mix929.com · wdez.com · jack1065.com · wsau.com
- [● 12 SOURCES] AstraZeneca aims to generate $80 billion in annual revenue by 2030, counting on up to 20 new drug launches. www.pharmabiz.net · mix929.com · wdez.com · jack1065.com · entrevue.fr · +6 more