Barriers to HIV Pre-exposure Prophylaxis access identified in US and South Africa

Research studies in the United States and South Africa have identified various barriers to the uptake and integration of HIV pre-exposure prophylaxis (PrEP) within different healthcare contexts.

In the United States, a study focusing on Black men who have sex with men (BMSM) in HIV hotspots identified individual, sociocultural, and structural obstacles. Key barriers included misinformation, concerns regarding side effects, and low perceived risk. Additionally, stigma, PrEP shaming, affordability, and non-affirming interactions with healthcare providers were cited as significant impediments to access.

In South Africa, research conducted in the North West Province examined the integration of PrEP into primary healthcare services. The study highlighted the need for better resource investment and compliance with clinical guidelines to ensure effective service delivery. Findings emphasized the importance of awareness, the role of stigma, and the necessity of addressing specific contextual factors to achieve equitable access and sustained use of the prophylaxis.