Brno scientists develop mussel-inspired bone adhesive

Researchers at CEITEC, part of the Brno University of Technology, have developed an innovative, absorbable bone adhesive inspired by the proteins used by mussels to adhere to surfaces in wet environments. The material consists of two components: a sticky gel and a bioceramic powder. When mixed, it forms a porous substance that mimics real bone structure.

This porosity allows nutrients, blood, and stem cells to pass through the material. Over time, the patient's own cells grow into the adhesive, eventually transforming it into natural bone. The adhesive can be applied via injection, allowing for even distribution and the ability to secure small bone fragments under X-ray guidance without extensive surgery.

Doctors may also be able to add antibacterial or healing agents to the mixture. The project is currently undergoing preclinical testing on sheep models in collaboration with experts from Brno University Hospital and other research institutes. The research team is currently seeking industrial partners to fund the next stages of testing, which are estimated to cost tens to hundreds of millions of crowns.