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Cabergoline drug may reduce breast cancer risk, study finds
An international team of researchers has identified that cabergoline, a medication used to suppress lactation, may significantly reduce the risk of breast cancer. The findings, published in the journal Cancer Discovery, are based on an analysis of medical records from over 150,000 women in Spain and Norway, as well as laboratory studies involving mice.
In the human data analysis, women under the age of 50 who used cabergoline to halt milk production after childbirth were approximately 70 per cent less likely to develop breast cancer compared to those who did not use the drug.
In animal models, researchers found that a single dose of cabergoline administered at the end of lactation reduced tumor incidence by about half in mice carrying BRCA1 and TP53 mutations. The drug appears to assist in mammary involution, the natural biological process where the breast clears excess milk-producing tissue. In mice, the medication was shown to reduce precancerous tissue, inhibit cell growth, and increase the presence of tumor-fighting immune cells.
Entities
Cancer Discovery · Cancer Research Center in Salamanca · Christopher Maxwell · Spain · University of British Columbia
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 3 SOURCES] A single dose of cabergoline reduced tumor incidence rates by about half in mice with BRCA1 and TP53 mutations. news.ubc.ca · www.telesurenglish.net · www.upday.com
- [● 2 SOURCES] Cabergoline helps complete the mammary involution process, which is the natural clearing of excess tissue after lactation ends. www.telesurenglish.net · www.upday.com
- [● 2 SOURCES] Women using cabergoline to suppress milk production were approximately 70 per cent less likely to develop breast cancer. news.ubc.ca · www.upday.com
- [● 3 SOURCES] Cabergoline may reduce the risk of breast cancer when used to suppress milk production after childbirth. news.ubc.ca · www.telesurenglish.net · www.upday.com
- [○ 1 SOURCE] In mouse models, cabergoline reduced precancerous tissue and increased the presence of immune cells defending against tumors. www.telesurenglish.net