started · updated
Cancer research reveals early detection markers and rising early-onset trends
Researchers have identified biological markers in blood that may signal certain cancers years before clinical diagnosis. A study conducted by the University of Oxford and the University of Toronto analyzed stored blood samples to examine DNA methylation—chemical changes that affect gene expression. The most significant findings involved prostate cancer, where specific patterns were detectable between five and eight years before diagnosis. While traces were also found in breast cancer cases, the signals were less distinct.
Separately, a Nordic study involving data from 2.2 million cases has revealed a concerning rise in early-onset cancer among adults under 50. Between 2003 and 2022, the incidence of 12 out of 18 common cancer types increased. The most significant annual increases, exceeding 2.5 percent, were observed in thyroid, colorectal, and kidney cancers. Researchers from Karolinska Institutet noted that increases in colorectal and breast cancer were particularly pronounced among individuals under 35, raising concerns about long-term health risks for younger generations.
Entities
Karolinska Institutet · University of Oxford · University of Toronto