Cannabidiol shows potential in breast cancer research

Recent research has explored the potential of cannabidiol (CBD) in treating various forms of breast cancer, specifically focusing on its effects when combined with standard therapeutic agents.

A study conducted by researchers at Ondokuz Mayıs University investigated the impact of CBD on HER2-positive breast cancer cells. The findings indicated that CBD produced a dose-dependent reduction in cancer cell proliferation and significantly reduced HER2 gene expression. When CBD was combined with the drug trastuzumab, the antiproliferative effect was significantly greater than using either treatment alone at certain concentrations.

Another study examined the interaction between CBD and Tamoxifen in hormone-dependent breast cancer cells. This research focused on how co-treatment affects macrophage polarization and the stem-like properties of tumor cells. The study aimed to address drug resistance and tumor recurrence by investigating whether CBD can mitigate pro-tumorigenic interactions within the tumor microenvironment.