CBD oil research examines health benefits and liver safety

CBD (cannabidiol), a compound found in Cannabis sativa, is increasingly used for managing stress, sleep, and pain. Unlike THC, the World Health Organization notes that pure CBD does not exhibit psychoactive effects or significant potential for abuse.

Recent research published in JAMA Internal Medicine, funded by the U.S. Food and Drug Administration, investigated the impact of CBD on liver health. The study monitored 200 healthy adults receiving daily doses of 5 mg per kilogram of body weight for one month. While a small number of participants showed increased liver enzymes—indicators of potential liver stress—the levels subsided after discontinuing CBD use, suggesting the effect may be short-term.

Experts suggest that individuals consuming high daily doses, such as 300–400 mg, should periodically monitor liver function, especially if they consume alcohol, have existing liver issues, or take other medications. Most commercially available products contain much lower doses, typically between 5–30 mg, which are considered safer for the average user.