Celiac disease: health warnings in Mexico and new research on gut immune response

Health experts at the Universidad Autónoma de San Luis Potosí warn that celiac disease may affect about one percent of the Mexican population, yet most cases remain undiagnosed. Nutritionist Miguel Ángel Mejía Díaz stresses that symptoms such as diarrhea, abdominal pain and weight loss are often mistaken for other digestive issues, leading to delayed diagnosis. He advises that confirmation requires medical testing, and that lifelong adherence to a strict gluten‑free diet is the only effective treatment.

A separate scientific review published in Frontiers in Immunology by researchers from the University of Rome Tor Vergata synthesises evidence on how gluten triggers an immune cascade in the small intestine. The paper highlights the role of tissue transglutaminase 2, genetic predisposition, gut‑microbiota imbalance and amplified immune signaling that together cause tissue damage. Understanding these mechanisms could inform future therapeutic approaches beyond the current gluten‑free diet.