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Charité Berlin treats first German patient with CRISPR gene-editing
For the first time in Germany, a patient has been successfully treated using CRISPR gene-editing technology at Charité in Berlin. The 19-year-old patient, Mohammed, was treated for Beta-thalassemia, a genetic blood disorder.
According to Charité, the treatment with the medication Casgevy has rendered the patient independent of regular blood transfusions. Medical staff reported that his immune system has regenerated and his current health status is excellent. The patient will remain under observation for the next 15 years.
Casgevy has been approved in the European Union since 2024 for patients aged 12 and older suffering from sickle cell disease and Beta-thalassemia. These conditions involve defects in the hemoglobin gene, which is essential for oxygen transport in red blood cells. Severe Beta-thalassemia is life-threatening and affects approximately 60,000 children born globally each year.
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 3 SOURCES] The patient's immune system has regenerated and his health is reported to be excellent. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] The drug Casgevy has been approved in the European Union since 2024 for patients aged 12 and older with sickle cell disease or Beta-thalassemia. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] The 19-year-old patient, Mohammed, no longer requires blood transfusions for Beta-thalassemia following the treatment. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] The patient will be monitored for 15 years following the treatment. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] A patient in Germany has been successfully treated using CRISPR gene-editing technology. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] The patient's immune system has regenerated and his current health is reported as excellent. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] A patient in Germany has been successfully treated with a CRISPR-based gene-editing medication for the first time. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] The medication used, Casgevy, has been approved in the European Union since 2024 for treating sickle cell disease and Beta-thalassemia in patients aged 12 and older. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] Approximately 60,000 children are born worldwide each year with severe Beta-thalassemia. www.kurierverlag.de · www.leinetal24.de · www.onetz.de
- [● 3 SOURCES] The 19-year-old patient, Mohammed, no longer requires blood transfusions following the treatment for Beta-thalassemia. www.kurierverlag.de · www.leinetal24.de · www.onetz.de