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[HEALTH] · United States, Australia, New Zealand · 9 sources

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Part of situation: CRISPR gene-editing therapy for cholesterol reduction (3 clusters)

Gene-editing treatment reduces cholesterol by 50% for over one year

gene editing cholesterol reduction CRISPR-Cas9 cardiovascular disease clinical trial

Scientists have reported that a single-dose gene-editing treatment using CRISPR-Cas9 can significantly and durably reduce cholesterol levels. Results from a small pilot study of 15 patients, published in The New England Journal of Medicine, indicate that the intervention may offer a long-term solution for managing high cholesterol.

In the group receiving the highest dose, patients experienced an approximately 50% reduction in LDL (bad) cholesterol and a substantial decrease in triglycerides. Follow-up data showed that these reductions, which were evident 60 days after the infusion, persisted for more than one year without significant adverse effects.

Researchers from the United States, Australia, and New Zealand emphasize that while these preliminary results are promising, larger clinical trials are necessary to confirm the safety and efficacy of the treatment before it becomes a standard medical option.

Entities

CRISPR-Cas9 · Cleveland Clinic · Dr. Luke Laffin · Dr. Steven Nissen · Luke Laffin · New England Journal of Medicine · Steven Nissen

Claims

What the coverage asserts, and how many sources carry each claim.

Sources

Tratamento experimental pode reduzir por meses uma substância ligada a infarto e AVC | CNN Brasil [www.cnnbrasil.com.br]
14 days ago
Mediante la modificación de un gen, los científicos esperan eliminar el colesterol alto de por vida [abc17news.com]
15 days ago
L'avanç que pot canviar el colesterol: una teràpia genètica aconsegueix reduir-lo un 50% [www.catalunyapress.cat]
15 days ago
Un tratamiento experimental de una sola vez redujo drásticamente el colesterol durante un año [diario.mx]
15 days ago
Novo remédio de dose única promete reduzir o colesterol por um ano [dol.com.br]
15 days ago
Zbulohet trajtimi që ul kolesterolin e keq me rreth 50% për një vit [javanews.al]
13 days ago
Mediante la modificación de un gen, los científicos esperan eliminar el colesterol alto de por vida [keyt.com]
15 days ago
With the snip of a gene, scientists hope to erase high cholesterol for life [kioncentralcoast.com]
15 days ago
Mediante la modificación de un gen, los científicos esperan eliminar el colesterol alto de por vida [localnews8.com]
15 days ago