Creatine Shows Promise in Cancer Immunotherapy Amid Ongoing Supplement Popularity

A preclinical study conducted by researchers at the University of California, Los Angeles (UCLA) reported that creatine can serve as an energy source for immune cells. In mouse models of melanoma, creatine supplementation activated dendritic cells and T‑cells, slowing tumor growth. The findings suggest a potential new avenue for cancer immunotherapy, although human trials are still needed.

Separately, creatine continues to be widely used as a dietary supplement for athletic performance. Scientific reviews confirm that it enhances short‑duration, high‑intensity activities by rapidly replenishing ATP, leading to increased strength, power output, and muscle mass. Its benefits for endurance sports are limited, and research into effects on brain function is ongoing.