Endometriosis risk may be linked to genetic and epigenetic factors

Medical experts are warning that severe or persistent period pain should not be dismissed as a normal part of menstruation, as it may indicate endometriosis. This chronic condition, which affects approximately 1 in 10 women and girls, involves uterine-like tissue growing outside the uterus and can lead to pelvic pain, infertility, and a diminished quality of life.

Research suggests that genetic and epigenetic factors, such as DNA methylation and histone modifications, play a significant role in a person's susceptibility to the disease. In India, diagnostic delays are a major concern, with many women waiting between seven and ten years for a formal diagnosis due to a lack of early identification tools.

Dr. Priti Arora Dhamija of the Sitaram Bhartia Institute of Science and Research noted that India's complex health system and lack of referral structures can increase the financial and logistical burden on patients navigating various providers.