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Excessive sugar intake linked to dementia risk
Dr. Kenju Shimomura, a medical researcher and physician, warns that excessive sugar consumption is a significant risk factor for dementia and Alzheimer's disease. In his work, he describes a condition termed ‘sugar-toxic brain’ (糖毒脳), where long-term overconsumption of sugar disrupts insulin function.
While insulin is commonly known for regulating blood sugar, it also plays a critical role in the brain by facilitating communication between neurons and protecting them from attacks by amyloid-beta. When insulin resistance develops due to chronic high sugar intake, the brain loses this protective mechanism, increasing the risk of cognitive decline.
Shimomura notes that many people mistakenly believe they are safe if they avoid sweets. However, significant amounts of sugar are hidden in non-sweet foods such as rice, bread, noodles, crackers, and potatoes. Maintaining brain health requires monitoring these ‘hidden carbohydrates’ to prevent long-term neurological damage.
Entities
Fukushima Medical University · Kenju Shimomura · University of Oxford