Gastric cancer research identifies sex and gender differences

A systematic review led by researchers from Hospital Clínic de Barcelona, the University of Barcelona, IDIBAPS, and CIBEREHD has identified significant differences in gastric cancer based on biological sex and gender. Analyzing 38 international studies involving over 500,000 patients, the research indicates that men and women exhibit different incidence rates, distinct biological tumor characteristics, specific risk factors, and unequal clinical progression.

Dr. Sabela Carballal, a lead author, emphasized that incorporating sex and gender perspectives is essential for providing precise, personalized, and equitable medical care.

In a separate context regarding gastric cancer risk, data indicates that approximately 90% of cases are associated with Helicobacter pylori infection. While the bacteria is present in a large portion of the population, only a minority of infected individuals develop chronic gastritis, peptic ulcers, or gastric cancer. Other contributing risk factors include high salt consumption, smoked foods, processed meats, and smoking.