College football features major matchups including Georgia vs. Oklahoma and Oregon vs. USC

Major college football matchups are scheduled for the weekend of September 26, 2026, featuring several high-profile contests across various conferences.

In the SEC, No. 2 Georgia prepares to host Oklahoma. Georgia enters the game with a 3-0 record and a top-ranked scoring offense, while Oklahoma looks to leverage its defense and quarterback John Mateer, whom Georgia coach Kirby Smart noted for his athleticism and ability to make plays with both his legs and arms.

In the Big Ten, No. 20 Oregon travels to face No. 12 USC at the Los Angeles Memorial Coliseum. Both teams boast highly productive offenses, averaging over 500 total yards per game. Oregon enters as a slight favorite in the matchup.

Other notable games include Boise State facing Western Michigan, and Oklahoma State traveling to West Virginia. Additionally, Tulsa prepares for a Week 4 matchup against Arkansas, though they may be without starting quarterback Baylor Hayes due to a knee injury.

Ball State is set to begin Mid-American Conference play with a road game against Kent State, with head coach Mike Uremovich emphasizing the need to reduce penalties.