Griffith University researchers develop breath analysis for lung cancer detection

Researchers at Griffith University have developed a method to distinguish between malignant and benign lung nodules using breath analysis. The study, published in MedComm, utilizes eNose technology to identify chemical signatures in breath, combined with gas chromatography-mass spectrometry (GC-MS) to pinpoint specific volatile organic compounds.

Professor Chamindie Punyadeera noted that this dual approach performs significantly better than models relying solely on standard clinical information. While the method is not intended to replace traditional biopsies—which can be technically difficult or carry risks like pneumothorax—it serves as a non-invasive tool to help doctors identify which patients require urgent invasive intervention.

Lung cancer affects approximately 2.5 million people globally each year. This technology aims to support early detection and streamline the diagnostic process for small or hard-to-reach lesions.