Houston Cougars favored to defeat Southern University in Week 2

The Houston Cougars are favored to win their Week 2 college football matchup against the Southern University Jaguars at TDECU Stadium. Houston enters the game as a 51.5-point favorite, with analysts predicting a low-scoring affair due to the Cougars' defensive strength and head coach Willie Fritz’s tendency to manage the clock and preserve starters during blowouts.

Southern University, coming off a loss to Alabama State and a win against Kentucky State, relies on quarterback Christian Johnson and running back Trey Holly to challenge the Houston defense. Key matchups include Southern’s Christian Johnson against Houston nickelback Javion White, and Southern’s Trey Holly against Houston linebacker Jaden Yates. Houston’s defensive performance in Week 1, where they limited Oregon State to 26 rushing yards, is expected to be a significant factor in the game.