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Influenza vaccination importance highlighted amid new vaccine research
Health experts are emphasizing the importance of annual influenza vaccinations as viruses continually evolve. The CDC reported that the 2024-25 U.S. flu season resulted in approximately 51 million illnesses, 710,000 hospitalizations, and 45,000 deaths. While vaccines may not prevent every infection, they are effective at reducing the risk of serious complications, particularly for high-risk groups such as adults over 65, young children, and pregnant individuals.
New developments in vaccine technology include the FDA approval of Moderna’s mFLUSIVA, the first mRNA flu vaccine for adults aged 50 and older. Additionally, scientific research published in Nature Immunology has identified a specific subset of monocytes that may play a critical role in strengthening vaccine efficacy. These cells appear to support the formation and survival of tissue-resident memory T cells in the lungs, which act as a first line of defense against respiratory infections.
Entities
Centers for Disease Control and Prevention · FDA · Moderna · University of Rochester Medicine