Insulin's 105th Anniversary Highlights Its Impact on Diabetes Care

In 1921 Canadian researchers Frederick Banting, Charles Best, John Macleod and James Collip discovered insulin, a breakthrough that turned diabetes from a fatal diagnosis into a manageable chronic condition. The first insulin extracts, derived from animal pancreas, gave patients with type 1 diabetes a real chance to live, work and raise families. Over the past century the therapy has evolved to human recombinant insulins and rapid‑acting analogues, while delivery technologies such as pumps, continuous glucose monitors and automated insulin delivery systems have further improved control and quality of life.

Despite these advances, diabetes remains a global health challenge, with more than 800 million people estimated to be living with the disease, many undiagnosed. Lifestyle changes and obesity continue to drive new cases, underscoring the ongoing need for prevention, early detection and access to effective insulin treatment.