Doc – Nelle tue mani returns for fourth season on Rai 1

The popular Italian medical drama ‘Doc – Nelle tue mani’ returns for its fourth season on Rai 1, premiering on October 1, 2026. The new season consists of eight episodes, totaling sixteen 50-minute segments. Produced by Lux Vide and Rai Fiction, the series follows Dr. Andrea Fanti, played by Luca Argentero, as he returns to the Ambrosiano hospital after a period away.

The plot introduces significant tension within the hospital, including economic difficulties, budget cuts that lead to a reduction in hospital beds, and suspicious deaths. Matilde Gioli returns as Dr. Giulia Giordano, who faces new professional challenges and responsibilities. Additionally, actress Cristina Marino joins the cast as Dr. Lidia Morganti, a locum doctor navigating the complexities of the medical staff.

Regarding the future of the series, Luca Argentero has addressed previous rumors about his departure. While earlier indications suggested the fourth season might be his last, the actor has expressed a desire to continue with the character, stating he would find it difficult to leave the role behind.