Lupus prevalence rises among women aged 20-40

Systemic Lupus Erythematosus (SLE), a chronic autoimmune disease where the immune system attacks healthy tissue, is increasingly being diagnosed in women aged 20 to 40. Approximately 90% of patients are female, particularly those of childbearing age, suggesting that female hormones may play a role in its development.

Common symptoms include persistent fatigue, fever, joint pain, muscle aches, hair loss, and unexplained weight loss. A signature dermatological sign is a butterfly-shaped rash across the cheeks and nose, though some patients only experience photosensitivity. If left unmanaged, the inflammation can spread to vital organs, including the kidneys (lupus nephritis), lungs, heart, and the central nervous system.

Professor Lee Young-ho of Korea University Anam Hospital emphasizes that while there is no cure, the goal of treatment is to control inflammation and prevent organ damage. Management strategies range from antimalarials and low-dose steroids for mild cases to immunosuppressants and biological agents for severe organ involvement. Early diagnosis through blood tests, such as the antinuclear antibody (ANA) test, and consistent lifestyle management—including regular exercise, balanced nutrition, and stress control—are critical for maintaining quality of life.