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Mayo Clinic study identifies gut microbiome signatures as potential cancer biomarkers
A Mayo Clinic study published in Cell has identified specific gut microbiome signatures that may serve as biomarkers for various cancers. By analyzing stool samples from 1,364 patients, researchers discovered distinct microbial patterns associated with five major cancer groups. Notably, the study found significant differences in patients diagnosed at younger ages, particularly regarding early-onset colorectal and breast cancers.
In patients aged 50 and younger with colorectal cancer, researchers observed higher lactate levels and an increase in the bacterium Veillonella parvula. Younger breast cancer patients showed changes across 64 bacterial species and lower levels of primary bile acids. These findings offer potential for predicting cancer progression and chemotherapy side effects.
Separately, research published in The Lancet Oncology by the International Agency for Research on Cancer (IARC) indicates that infectious agents play a major role in global cancer statistics. In 2024, an estimated 2.3 million cancer cases—approximately one in eight new diagnoses—were attributed to viruses, bacteria, or parasites.
Entities
Cell · International Agency for Research on Cancer · Mayo Clinic · Purna C. Kashyap · The Lancet Oncology
Claims
What the coverage asserts, and how many sources carry each claim.
- [○ 1 SOURCE] Infectious agents accounted for roughly one in eight new cancer diagnoses globally in 2024. www.fitbook.de
- [● 3 SOURCES] Unique microbiome signatures were found associated with five major cancer groups. www.fehmarn24.de · www.kurierverlag.de · www.leinetal24.de
- [● 3 SOURCES] Colorectal cancer patients aged 50 and younger showed higher lactate levels and increased amounts of Veillonella parvula. www.fehmarn24.de · www.kurierverlag.de · www.leinetal24.de
- [● 3 SOURCES] Researchers analyzed stool samples from 1,364 cancer patients to identify microbiome patterns linked to various cancers. www.fehmarn24.de · www.kurierverlag.de · www.leinetal24.de
- [● 3 SOURCES] Younger breast cancer patients exhibited changes in 64 bacterial species and lower primary bile acid levels. www.fehmarn24.de · www.kurierverlag.de · www.leinetal24.de
- [○ 1 SOURCE] Approximately 2.3 million cancer cases in 2024 were linked to viruses, bacteria, or parasites. www.fitbook.de