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[HEALTH] · Sweden, Norway · 3 sources

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Medical breakthrough offers hope for type 1 diabetes cure

Researchers at Akademiska sjukhuset in Uppsala have reported a medical breakthrough regarding the treatment of type 1 diabetes. For the first time, a patient has received a transplant of gene-modified cells capable of producing insulin without the need for concurrent immunosuppressive medication.

In the study, a man in his 40s was transplanted with insulin-producing cells derived from a deceased donor. These cells were genetically modified at a university hospital in Oslo to ensure the recipient's immune system does not recognize and reject them. This modification is significant because traditional transplants typically require lifelong immunosuppressive drugs, which carry risks of infection and cancer.

The patient has been monitored for 14 months, and the results, published in the New England Journal of Medicine, indicate that the cells successfully produced insulin. Lead researcher Per-Ola Carlsson stated that the hope is for this technology to transform type 1 diabetes from a chronic condition into a curable one. Future research will focus on testing the method with larger quantities of cells.

Entities

Akademiska sjukhuset · New England Journal of Medicine · Oslo University Hospital · Per-Ola Carlsson