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[HEALTH] · Brazil · 6 sources

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Medical experts warn of risks and weight regain with obesity medications

Medical experts are warning about the risks of using obesity medications like tirzepatide and semaglutide without professional supervision. While these drugs are effective for weight loss, improper use can lead to side effects such as nausea, vomiting, dehydration, and hypoglycemia. Rapid weight loss also poses a risk of losing muscle mass instead of fat.

Specialists emphasize that nutritional deficiencies are a significant concern. Because these medications reduce appetite, patients may consume insufficient amounts of essential nutrients, including proteins, iron, vitamin B12, vitamin D, and calcium. Medical monitoring is necessary to adjust dosages safely and evaluate reproductive health and body composition.

Furthermore, research published in the BMJ indicates that weight regain is a common occurrence after discontinuing treatment. Data suggests an average weight increase of 0.4 kg per month following the cessation of medication. Experts explain that obesity is a chronic condition, and stopping medication without implementing long-term lifestyle changes—such as regular exercise and dietary adjustments—often triggers biological mechanisms that favor weight accumulation.

Entities

BMJ · Einstein Hospital Israelita