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[HEALTH] · Spain, United States · 2 sources

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Mental health and childhood trauma linked to increased dementia and stroke risks

New research highlights the complex links between mental health, early life experiences, and long-term neurological risks. A study published in the Journal of Neuroscience by researchers at Temple University and the University of Oregon suggests that childhood trauma may contribute to dementia risk through its impact on brain connectivity. The study found that trauma alone does not predict anhedonia—the loss of motivation and pleasure—but rather the combination of early adversity and disrupted communication between the hippocampus and motivation-related pathways.

Separately, a large-scale study conducted in Catalonia, Spain, involving nearly 700,000 individuals, found that severe mental illnesses, such as schizophrenia, bipolar disorder, and major depression, are significantly associated with increased risks of dementia and stroke. The research noted that while dementia remains relatively uncommon in younger populations, the relative risk is notably higher for those with severe psychiatric diagnoses, particularly among adults aged 30 to 39. These findings suggest that medical professionals may need to monitor cardiovascular and brain health much earlier in patients with serious mental health conditions.

Entities

Journal of Neuroscience · Temple University · University of Oregon