Midlife Weight‑Loss Hurdles Tied to Protein Timing and Hormone Testing

Chief medical officer Dr. Alan Farrell warns that many people over 40 struggle to lose weight because they concentrate protein intake at dinner, leaving earlier meals low in protein. research indicates that spreading protein throughout the day better supports muscle protein synthesis, which is crucial for maintaining resting energy expenditure, especially as anabolic resistance increases with age.

Separately, hormone specialists note that standard testosterone tests can miss low bioavailable testosterone or elevated SHBG, conditions that impede muscle maintenance and fat loss in both men and women after 40. Even when total testosterone appears normal, insufficient active hormone can prevent effective body‑composition changes despite proper diet and exercise.