Muscle loss linked to 42% higher dementia risk in new study

An international research study led by Curtin University has found that sarcopenia—the age-related loss of muscle mass, strength, and physical function—is linked to a 42 per cent higher risk of developing dementia.

By analyzing more than 80 studies, researchers identified a complex relationship between body weight, obesity, and dementia risk that varies by age. Obesity in individuals under the age of 65 was associated with a 9 per cent increase in dementia risk. Conversely, obesity in those aged 65 and older was linked to a 17 per cent lower risk.

Lead researcher Dr. Uraiporn Booranasuksakul from Burapha University noted that body weight alone does not provide a complete picture of health, emphasizing that maintaining muscle strength and function is vital during aging. Professor Mario Siervo of Curtin University cautioned that the lower risk observed in older obese individuals should not be interpreted as a recommendation to gain weight, but rather highlights the intricate connection between aging and body composition. Further long-term research is required to understand how muscle mass and body fat interact regarding dementia risk.