NBA Matchups: Nuggets vs. Thunder and Cavaliers vs. 76ers

Several NBA matchups are scheduled for October 22, 2026. In Oklahoma City, the Denver Nuggets face the OKC Thunder at the Paycom Center. The Thunder enter the matchup following roster adjustments designed to accommodate ascending young talent, while the Nuggets have undergone minor offseason roster tweaks.

In Philadelphia, the 76ers host the Cleveland Cavaliers at Xfinity Mobile Arena. The 76ers are coming off an opening victory featuring LeBron James and Jaylen Brown. The Cavaliers are debuting a lineup featuring the duo of Donovan Mitchell and James Harden, following Harden's recent contract signing with the team.