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[HEALTH] · Taiwan · 2 sources

NCKU Hospital treats over 100 Alzheimer's patients with new drugs

The Dementia Center at National Cheng Kung University (NCKU) Hospital has reported clinical progress using new anti-amyloid drugs, lecanemab and donanemab, to treat Alzheimer's disease. Since the first case began on June 23, 2025, the hospital has treated more than 100 patients.

Amyloid PET scans conducted during follow-ups indicate a significant reduction in amyloid load in nearly all treated cases, with some patients meeting specific amyloid clearance standards. Clinical observations from families also suggest improvements in cognitive function, social interaction, and daily life participation for some patients.

Medical staff noted that while most side effects, such as flu-like symptoms, were manageable, a small number of patients showed microhemorrhages on brain MRIs. These instances did not result in clinical symptoms, and the hospital continues to monitor patients via brain imaging and clinical assessments to ensure safety. Experts emphasize that these drugs aim to slow disease progression rather than provide a cure, and are most effective when used in the early stages of the disease.

Entities

NCKU Hospital Dementia Center · National Cheng Kung University Hospital · donanemab · lecanemab

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