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Nutritional studies link elderberry juice to lower glucose and fructose to increased liver fat

Recent nutritional studies have highlighted the distinct metabolic impacts of different sugars and fruit extracts. A study published in the journal ‘Nutrients’ found that consuming approximately 340 ml of elderberry juice daily for one week resulted in an average 24 percent reduction in glycemic response. Researchers suggest that anthocyanins, the pigments responsible for the fruit's dark color, may slow carbohydrate digestion by limiting enzyme activity, similar to the mechanism of certain diabetes medications. However, researchers noted that the short duration of the study means long-term effects remain unconfirmed.

Separately, research published in the ‘Journal of Hepatology’ examined the effects of sweetened beverages on liver health. In a randomized controlled trial involving 94 healthy men, researchers found that daily consumption of beverages sweetened with fructose or sucrose significantly increased hepatic de novo lipogenesis—the production of new fat in the liver. Specifically, these beverages led to a twofold increase in the hepatic secretion rate compared to a control group. Notably, glucose-sweetened beverages did not produce this same effect, even when total energy intake remained similar across groups, suggesting a specific metabolic reaction to fructose and sucrose.

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Journal of Hepatology · Nutrients