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[HEALTH] · Italy · 3 sources

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Obesity treatments evolve toward weekly injections and oral therapies

Medical experts at the Italian Obesity Society's national congress in Palermo discussed the rapid evolution of obesity treatments. The field is transitioning from daily injections to weekly doses, with oral therapies on the horizon. Notably, the European Medicines Agency (EMA) has approved the molecule orforglipron, which is expected to reach commercial markets soon.

New obesity medications, specifically those based on incretins, offer benefits beyond weight loss, including improved cardiovascular health and reduced risks of fatty liver and sleep apnea. However, experts warn that obesity is a chronic condition; stopping treatment abruptly can lead to weight regain, necessitating long-term management alongside diet and exercise.

In Italy, where approximately 46% of adults are overweight or obese, access to these treatments remains a challenge due to high costs. While long-term safety is generally supported, ongoing studies continue to evaluate potential oncological risks.

Entities

European Medicines Agency · Lilly · Palermo · Paolo Sbraccia · Società Italiana dell'Obesità

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