Olivia Ninotti Highlights Brain Fatigue From Modern, High‑Speed Lifestyle

Neuropsychiatrist Olivia Ninotti explains that many people feel chronically exhausted even with adequate sleep because the human brain is not built to process an endless stream of decisions, notifications and emotional stimuli. The prefrontal cortex consumes about 20 % of the body’s energy, and each minor interruption forces costly metabolic activity, diminishing attention and memory.

Sleep specialist Luigi Ferini Strambi adds that insufficient sleep disrupts hormonal cycles essential for health. Lack of restorative sleep raises cortisol, triggers systemic inflammation, and increases risks of insulin resistance, hypertension, anxiety, depression and cognitive decline. A recent controversial comment by Japanese premier Sanae Takaichi, claiming she sleeps only two to three hours, sparked debate about the limits of productivity‑driven sleep deprivation.