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[HEALTH] · United States · 2 sources

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Oral health linked to increased Alzheimer's risk

Scientific research is investigating a potential link between periodontal disease and the development of Alzheimer's disease. Studies suggest that individuals with gum disease lasting at least ten years may face double the risk of developing this neurodegenerative condition.

A study published in the journal Science Advances identified the bacterium Porphyromonas gingivalis (P. gingivalis) in the brains of people suffering from Alzheimer's. This bacterium is directly associated with oral infections and gum care. Experiments conducted on mice further demonstrated that this specific bacterium can travel from the mouth to the brain, causing damage to nerve cells.

The research was funded by the founders of Cortexyme, an American pharmaceutical company focused on studying Alzheimer's and other neurodegenerative disorders.

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Cortexyme · Porphyromonas gingivalis · Science Advances