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Ovarian tissue remains biologically active after menopause, study finds
A study published in the journal Aging Cell reveals that ovaries remain biologically active and undergo significant changes long after menopause. Research led by Northwestern University and the Buck Institute for Research on Aging challenges the long-held scientific assumption that the organ becomes largely inactive after the end of fertility.
By analyzing 5,812 protein groups in the ovarian tissue of 28 women aged 50 to 75, researchers identified statistically significant differences in 117 proteins between women in their 50s and those aged 70 and older. While younger participants exhibited proteins related to cell maintenance and tissue structure, older participants showed increased markers for inflammation, immune responses, and tissue remodeling.
The findings suggest that the organ is highly dynamic, with protein levels rising or falling with age. This ongoing activity may influence other bodily systems, including the brain, heart, and immune system, though the long-term health implications of these post-menopausal changes remain unclear.
Entities
Aging Cell · Buck Institute for Research on Aging · Francesca Duncan · Northwestern University · Yale School of Medicine
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 2 SOURCES] Older women showed higher levels of proteins associated with inflammation, immune responses, and tissue remodeling. www.fehmarn24.de
- [● 2 SOURCES] The research team examined ovarian tissue from 28 women between the ages of 50 and 75. www.fehmarn24.de
- [● 2 SOURCES] The study analyzed 5,812 protein groups. www.fehmarn24.de
- [● 2 SOURCES] The study was led by researchers from Northwestern University and the Buck Institute for Research on Aging. www.fehmarn24.de
- [● 2 SOURCES] There were statistically significant differences in 117 proteins between women aged 50–59 and those aged 70 and older. www.fehmarn24.de
- [● 3 SOURCES] Ovaries remain biologically active and continue to change well into old age after menopause. www.fehmarn24.de