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Oxytocin nasal spray reduces acute stress before anesthesia
A randomized, double-blind study conducted at the General Hospital of Western Theater Command in Chengdu has found that intranasal oxytocin significantly reduces acute stress reactions in patients facing anesthesia for traumatic bone fractures.
The study involved 328 adults, with 164 participants receiving 40 International Units (IU) of oxytocin via nasal spray ten minutes before anesthesia induction, while the control group received a placebo. Results after three days showed that the oxytocin group had 15.9% fewer positive test results on the Stanford Acute Stress Reaction Questionnaire compared to the placebo group, representing a relative reduction of approximately 48%.
While the oxytocin spray effectively mitigated psychological stress, the data indicated no significant effects on postoperative pain, analgesic consumption, or cognitive performance.
Entities
Chengdu · General Hospital of Western Theater Command · Stanford Acute Stress Reaction Questionnaire
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- [○ 1 SOURCE] Oxytocin nasal spray was administered ten minutes before anesthesia induction. www.it-boltwise.de
- [○ 1 SOURCE] The study was conducted at the General Hospital of Western Theater Command in Chengdu. www.it-boltwise.de
- [○ 1 SOURCE] Oxytocin administration did not significantly affect postoperative pain or analgesic consumption. www.it-boltwise.de
- [○ 1 SOURCE] The oxytocin group showed a 14.6 percentage point difference in Stanford Acute Stress Reaction Questionnaire results compared to the placebo group. www.it-boltwise.de
- [○ 1 SOURCE] The study involved 328 adults. www.it-boltwise.de